Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sws
Flybase description The gene swiss cheese is referred to in FlyBase by the symbol Dmel\sws (CG2212, FBgn0003656).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.7669 1.0674 -1.024851 -1.7468 -3.339334 -4.64 -3.34228 -2.822234
    Affimetrix absolute value 6.506 7.712 7.502 7.595 7.095 6.383 6.868 6.865
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: lysophospholipase activity.
There is experimental evidence that it is involved in the biological process: membrane lipid metabolic process; phosphatidylcholine metabolic process; cellular membrane organization; sensory perception of smell; neuron apoptosis.
20 alleles are reported.
The phenotypes of these alleles are annotated with: cortex of lamina; epithelial glial cell; CNS glial cell; neuropil; eye photoreceptor cell; adult brain.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Acyl transferase/acyl hydrolase/lysophospholipase; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; Lysophospholipase patatin, conserved site; Patatin/Phospholipase A2-related; RmlC-like jelly roll fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.