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|Flybase description||The gene thickveins is referred to in FlyBase by the symbol Dmel\tkv (CG14026, FBgn0003716).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transforming growth factor beta receptor activity, type I; transforming growth factor beta binding.
There is experimental evidence for 23 unique biological process terms, many of which group under: anatomical structure development; biological regulation; regulation of developmental process; regulation of biological process; regulation of multicellular organismal development; cellular process involved in reproduction; organ development; cellular component organization or biogenesis; localization; multicellular organismal reproductive process; post-embryonic organ morphogenesis.
113 alleles are reported.
The phenotypes of these alleles are annotated with 88 unique terms, many of which group under: organ system subdivision; adult segment; organ system; adult mesothoracic segment; primordium; late extended germ band embryo; embryonic/larval tracheal system; nervous system; non-connected developing system; germarium; egg; synapse; external compound sense organ.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; TGF beta receptor, GS motif; TGF-beta receptor/activin receptor, type I/II.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.