Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ttk
Flybase description The gene tramtrack is referred to in FlyBase by the symbol Dmel\ttk (CG1856, FBgn0003870).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.6474 -1.6143 -4.612125 -3.4377 -7.78891 -3.2936 -3.22078 -6.471538
    Affimetrix absolute value 7.009 6.965 6.015 6.618 5.886 6.844 6.903 5.726
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: RNA polymerase II core promoter proximal region sequence-specific DNA binding; protein binding; chromatin binding; protein homodimerization activity.
There is experimental evidence for 21 unique biological process terms, many of which group under: anatomical structure development; biological regulation; open tracheal system development; cellular component organization or biogenesis; sensory organ development; cellular process involved in reproduction; compound eye photoreceptor development; organ morphogenesis; regulation of developmental process; compound eye cone cell differentiation; neuromuscular process; behavioral interaction between organisms; locomotion; growth.
156 alleles are reported.
The phenotypes of these alleles are annotated with 80 unique terms, many of which group under: organ system subdivision; external compound sense organ; nervous system; adult segment; peripheral nervous system; multi-cell-component structure; presumptive embryonic/larval nervous system; cuticle; imaginal precursor; eo support cell; taenidial fold; larval abdominal segment 5.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: AT hook, DNA-binding motif; BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 06-18 hour embryonic stages.