|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene tailup is referred to in FlyBase by the symbol Dmel\tup (CG10619, FBgn0003896).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: RNA polymerase II regulatory region sequence-specific DNA binding; protein binding; RNA polymerase II enhancer sequence-specific DNA binding; sequence-specific enhancer binding RNA polymerase II transcription factor activity; RNA polymerase II activating transcription factor binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; organ development; embryonic development via the syncytial blastoderm; regulation of cellular macromolecule biosynthetic process; sensory organ development; locomotion; anterior/posterior axis specification; notum cell fate specification; tripartite regional subdivision; lymph gland development; tissue homeostasis.
21 alleles are reported.
The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: organ system subdivision; synaptic neuropil subdomain; adult segment; antennal segment; multi-cell-component structure; cephalopharyngeal skeleton; adult mesothoracic segment; pharyngeal sclerite; appendage segment; extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Zinc finger, LIM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.