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|Flybase description||The gene twist is referred to in FlyBase by the symbol Dmel\twi (CG2956, FBgn0003900).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein heterodimerization activity; protein homodimerization activity; DNA binding.
There is experimental evidence that it is involved in the biological process: mesodermal cell fate commitment; muscle fiber development; Malpighian tubule morphogenesis; regulation of striated muscle tissue development; actomyosin structure organization; salivary gland morphogenesis; mesoderm development.
57 alleles are reported.
The phenotypes of these alleles are annotated with 32 unique terms, many of which group under: organ system; primordium; adult segment; portion of tissue; late extended germ band embryo; adult mesothoracic segment; non-connected developing system; organ system subdivision; germ layer; adult somatic muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Twist.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.