Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name w
Flybase description The gene white is referred to in FlyBase by the symbol Dmel\w (CG2759, FBgn0003996).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.0779 -11.5564 -16.723706 -23.4278 -21.607735 -22.0684 -13.91471 -15.128815
    Affimetrix absolute value 5.253 4.162 4.13 3.867 4.331 4.108 4.759 4.324
    Affymetric present call in "x" number of chips 3 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled to transmembrane movement of substances.
There is experimental evidence that it is involved in the biological process: cellular biogenic amine biosynthetic process; memory; compound eye pigmentation; cGMP transport; male courtship behavior; ommochrome biosynthetic process.
1790 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; portion of tissue; external compound sense organ; Malpighian tubule; integumentary plate; nervous system; adult; sensillum; compound cell cluster organ; Malpighian tubule segment; embryonic/larval excretory system; adult cuticle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; ATPase, AAA+ type, core; Pigment precursor permease.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period.