Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Zw
Flybase description The gene Zwischenferment is referred to in FlyBase by the symbol Dmel\Zw (CG12529, FBgn0004057).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.7815 3.8568 -0.978133 -4.8909 -2.553166 -3.1466 -1.18418 -1.392616
    Affimetrix absolute value 9.865 9.563 7.554 6.12 7.436 6.978 8.311 7.791
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glucose-6-phosphate dehydrogenase activity.
It is reported to be involved in the biological process: pentose-phosphate shunt.
122 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Glucose-6-phosphate dehydrogenase; Glucose-6-phosphate dehydrogenase, C-terminal; Glucose-6-phosphate dehydrogenase, NAD-binding; Glucose-6-phosphate dehydrogenase, active site; NAD(P)-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.