Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name oc
Flybase description The gene ocelliless is referred to in FlyBase by the symbol Dmel\oc (CG12154, FBgn0004102).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.3074 -28.2462 -44.979133 -56.8672 -67.244245 -62.2893 -61.24917 -47.60251
    Affimetrix absolute value 2.879 2.814 2.69 2.567 2.697 2.604 2.625 2.683
    Affymetric present call in "x" number of chips 0 0 1 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: ocellus photoreceptor cell development; positive regulation of gene expression; compound eye photoreceptor development; ocellus development; embryonic development via the syncytial blastoderm; positive regulation of transcription, DNA-dependent; rhabdomere development; brain segmentation.
40 alleles are reported.
The phenotypes of these alleles are annotated with 86 unique terms, many of which group under: organ system subdivision; embryonic/larval neuron; external compound sense organ; abdominal ventral denticle belt; VUM1 neuron; presumptive embryonic/larval nervous system; peripheral nervous system; integumentary plate; VUM2 neuron; commissure; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.