Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cdc2
Flybase description The gene cdc2 is referred to in FlyBase by the symbol Dmel\cdc2 (CG5363, FBgn0004106).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -28.0796 -12.5058 -12.92649 -13.0791 -13.587661 -6.9971 -30.28694 -12.969238
    Affimetrix absolute value 3.632 3.978 4.492 4.681 5.011 5.812 3.651 4.552
    Affymetric present call in "x" number of chips 0 2 1 3 2 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cyclin-dependent protein kinase activity; protein binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: cell cycle; anatomical structure development; cellular process involved in reproduction; cell cycle process; cell division; multicellular organismal reproductive process; response to DNA damage stimulus; macromolecule modification; biological regulation; interphase of mitotic cell cycle.
33 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; adult segment; organ system; imaginal precursor; somatic cell; nervous system; organelle; blastoderm embryo; cytoplasmic part; ganglion mother cell GMC4-2a; somatic stem cell; egg; cell cycle; dorsal thoracic disc.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.