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|Flybase description||The gene tinman is referred to in FlyBase by the symbol Dmel\tin (CG7895, FBgn0004110).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: cardioblast differentiation; gonadal mesoderm development; germ cell migration; embryonic heart tube development; pericardial cell differentiation; cardiac cell differentiation; lymph gland development; salivary gland morphogenesis; mesoderm development; cardiac muscle cell differentiation.
58 alleles are reported.
The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system; primordium; organ system subdivision; late extended germ band embryo; hypodermal muscle of larval abdomen; A1-7 transverse muscle; midgut constriction; embryonic/larval dorsal vessel; non-connected developing system; nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.