Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Csp
Flybase description The gene Cysteine string protein is referred to in FlyBase by the symbol Dmel\Csp (CG6395, FBgn0004179).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.4221 2.8928 1.871381 2.1921 1.307271 2.922 1.59219 1.036069
    Affimetrix absolute value 8.314 9.122 9.053 9.506 9.108 10.104 9.201 8.907
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: heat shock protein binding; unfolded protein binding.
There is experimental evidence that it is involved in the biological process: startle response; brain morphogenesis; exocytosis; locomotion involved in locomotory behavior.
57 alleles are reported.
The phenotypes of these alleles are annotated with: eye; interommatidial bristle; neuromuscular junction; embryonic/larval neuromuscular junction; wing; ommatidium.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Heat shock protein DnaJ; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages.