Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Syt1
Flybase description The gene Synaptotagmin 1 is referred to in FlyBase by the symbol Dmel\Syt1 (CG3139, FBgn0004242).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -23.6949 -18.0035 -26.147817 -27.3466 -36.232327 -34.1407 -27.15023 -29.106957
    Affimetrix absolute value 3.866 3.461 3.511 3.617 3.579 3.469 3.794 3.414
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 0 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: calcium ion-dependent exocytosis of neurotransmitter; neurotransmitter secretion; synaptic vesicle endocytosis; regulation of pole plasm oskar mRNA localization; regulation of synapse structure and activity; vesicle-mediated transport; larval locomotory behavior.
52 alleles are reported.
The phenotypes of these alleles are annotated with: neuron; neuromuscular junction; embryonic/larval neuromuscular junction; wing; synapse; synaptic vesicle; crystal cell.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; C2 region; Synaptotagmin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.