Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rdl
Flybase description The gene Resistant to dieldrin is referred to in FlyBase by the symbol Dmel\Rdl (CG10537, FBgn0004244).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.304 -12.1838 -15.765968 -18.6958 -24.895352 -26.1614 -20.11795 -18.180216
    Affimetrix absolute value 4.139 4.043 4.217 4.17 4.125 3.858 4.22 4.136
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: GABA-A receptor activity.
There is experimental evidence that it is involved in the biological process: response to mechanical stimulus; negative regulation of synaptic transmission; regulation of olfactory learning; regulation of circadian sleep/wake cycle; sleep.
33 alleles are reported.
The phenotypes of these alleles are annotated with: aCC neuron; RP2 neuron; U neuron; metathoracic intersegmental nerve; prothoracic intersegmental nerve; intersegmental nerve; mesothoracic intersegmental nerve; VUM neuron; abdominal intersegmental nerve.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Gamma-aminobutyric acid A receptor; Gamma-aminobutyric-acid A receptor, beta subunit; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed during early larval stages.