Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ptp4E
Flybase description The gene Protein tyrosine phosphatase 4E is referred to in FlyBase by the symbol Dmel\Ptp4E (CG6899, FBgn0004368).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.9345 -23.3501 -33.396564 -38.7587 -50.295562 -35.2663 -11.62405 -39.668269
    Affimetrix absolute value 3.167 3.082 3.115 3.121 3.12 3.431 5.021 2.939
    Affymetric present call in "x" number of chips 0 0 1 1 0 2 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transmembrane receptor protein tyrosine phosphatase activity.
There is experimental evidence that it is involved in the biological process: motor axon guidance; central nervous system development; open tracheal system development.
12 alleles are reported.
The phenotype of these alleles is annotated with: ventral nerve cord.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.