Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name neb
Flybase description The gene nebbish is referred to in FlyBase by the symbol Dmel\neb (CG10718, FBgn0004374).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -20.9708 -10.1651 -11.243274 -15.3782 -16.898992 -16.9872 -11.03324 -13.45851
    Affimetrix absolute value 4.039 4.286 4.691 4.469 4.701 4.487 5.182 4.517
    Affymetric present call in "x" number of chips 2 0 0 1 0 1 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein phosphatase 1 binding.
There is experimental evidence that it is involved in the biological process: mitotic chromosome condensation; mitotic cell cycle, embryonic; meiosis; ovarian follicle cell development; regulation of cell cycle.
51 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; external compound sense organ; organ system; nervous system; female germline cyst; adult segment; peripheral nervous system; sensillum; nuclear part; spermatozoon; cytoplasmic part; adult external prothorax.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Forkhead-associated (FHA) domain; Kinesin, motor domain; Kinesin, motor region, conserved site; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult male stages.