Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pdm2
Flybase description The gene POU domain protein 2 is referred to in FlyBase by the symbol Dmel\pdm2 (CG12287, FBgn0004394).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -36.1765 -3.3033 -12.02448 -3.2441 -12.098624 -2.8901 -21.1291 -8.331739
    Affimetrix absolute value 3.242 5.947 4.643 6.707 5.245 7.091 4.17 5.24
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: neuroblast development.
19 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: larval abdominal segment; organ system subdivision; nervous system; peripheral nervous system; embryonic/larval neuron; multicellular structure; somatic cell; organ system; embryonic abdomen; neuroblast NB4-2; ganglion mother cell GMC4-2a.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Lambda repressor-like, DNA-binding; POU; POU-specific.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.