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|Flybase description||The gene Cyclic-AMP response element binding protein A is referred to in FlyBase by the symbol Dmel\CrebA (CG7450, FBgn0004396).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: enhancer sequence-specific DNA binding; DNA binding.
There is experimental evidence that it is involved in the biological process: dorsal/ventral pattern formation; chitin-based larval cuticle pattern formation; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; larval chitin-based cuticle development; salivary gland development.
26 alleles are reported.
The phenotypes of these alleles are annotated with: larva; embryonic/larval salivary gland; ommatidium; embryonic/larval cuticle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Basic-leucine zipper (bZIP) transcription factor; Eukaryotic transcription factor, Skn-1-like, DNA-binding; bZIP transcription factor, bZIP-1; cAMP response element binding (CREB) protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.