|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene Multi drug resistance 49 is referred to in FlyBase by the symbol Dmel\Mdr49 (CG3879, FBgn0004512).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled; drug transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: response to hypoxia; response to methotrexate; germ cell migration.
8 alleles are reported.
The phenotype of these alleles is annotated with: pole cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like; ATPase, AAA+ type, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.