Flygut: an atlas of the Drosophila adult midgut

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Gene name Mdr49
Flybase description The gene Multi drug resistance 49 is referred to in FlyBase by the symbol Dmel\Mdr49 (CG3879, FBgn0004512).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.1609 2.3039 2.013238 -11.0268 -0.550437 2.0901 -4.38297 0.511663
    Affimetrix absolute value 5.071 8.802 9.119 4.975 8.504 9.582 6.644 8.445
    Affymetric present call in "x" number of chips 3 3 3 0 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled; drug transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: response to hypoxia; response to methotrexate; germ cell migration.
8 alleles are reported.
The phenotype of these alleles is annotated with: pole cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like; ATPase, AAA+ type, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.