Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name pros
Flybase description The gene prospero is referred to in FlyBase by the symbol Dmel\pros (CG17228, FBgn0004595).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.979 -7.3062 -10.51206 -15.7259 -25.16444 -10.3634 -55.96499 -20.681567
    Affimetrix absolute value 2.924 4.756 4.822 4.441 4.111 5.198 2.749 3.921
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; DNA binding.
There is experimental evidence for 24 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; regulation of multicellular organismal development; regulation of neurogenesis; localization; central nervous system development; cell division; neuroblast fate commitment; gliogenesis; sensory organ development; protein localization; system process.
168 alleles are reported.
The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: organ system subdivision; nervous system; peripheral nervous system; multi-cell-component structure; external compound sense organ; presumptive embryonic/larval nervous system; embryonic/larval glial cell; primordium; ventral nerve cord primordium; embryonic/larval neuron; commissure.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Homeo-prospero domain; Homeodomain-like; Prospero homeobox protein 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.