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|Flybase description||The gene prospero is referred to in FlyBase by the symbol Dmel\pros (CG17228, FBgn0004595).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; DNA binding.
There is experimental evidence for 24 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; regulation of multicellular organismal development; regulation of neurogenesis; localization; central nervous system development; cell division; neuroblast fate commitment; gliogenesis; sensory organ development; protein localization; system process.
168 alleles are reported.
The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: organ system subdivision; nervous system; peripheral nervous system; multi-cell-component structure; external compound sense organ; presumptive embryonic/larval nervous system; embryonic/larval glial cell; primordium; ventral nerve cord primordium; embryonic/larval neuron; commissure.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Homeo-prospero domain; Homeodomain-like; Prospero homeobox protein 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.