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|Flybase description||The gene Furin 2 is referred to in FlyBase by the symbol Dmel\Fur2 (CG18734, FBgn0004598).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: serine-type endopeptidase activity.
It is reported to be involved in the biological process: proteolysis.
10 alleles are reported.
No phenotypic data is available.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: Epidermal growth factor-like; Furin-like cysteine-rich domain; Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.