Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name zfh2
Flybase description The gene Zn finger homeodomain 2 is referred to in FlyBase by the symbol Dmel\zfh2 (CG1449, FBgn0004607).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.5281 -30.5394 -35.35629 -45.2045 -51.770212 -44.4246 -49.75572 -42.746161
    Affimetrix absolute value 2.896 2.708 3.035 2.893 3.064 3.089 2.934 2.834
    Affymetric present call in "x" number of chips 1 0 1 0 1 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: nervous system development; imaginal disc-derived wing morphogenesis.
12 alleles are reported.
The phenotypes of these alleles are annotated with: wing disc; sclerite; medial costal vein; alula; wing; wing vein L1; wing hinge.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.