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|Flybase description||The gene Phospholipase C at 21C is referred to in FlyBase by the symbol Dmel\Plc21C (CG4574, FBgn0004611).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: phosphatidylinositol phospholipase C activity.
There is experimental evidence that it is involved in the biological process: flight behavior.
16 alleles are reported.
The phenotype of these alleles is annotated with: adult olfactory receptor neuron Or59b.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; EF-hand-like domain; PLC-beta, C-terminal; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphoinositide phospholipase C; Phospholipase C, phosphatidylinositol-specific , X domain; Phospholipase C, phosphatidylinositol-specific, Y domain; Phospholipase C, phosphoinositol-specific, EF-hand-like; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.