Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name rho
Flybase description The gene rhomboid is referred to in FlyBase by the symbol Dmel\rho (CG1004, FBgn0004635).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -23.6592 -10.5742 -17.380791 -24.441 -31.530125 -21.7407 -38.85012 -17.516711
    Affimetrix absolute value 3.856 4.274 4.12 3.789 3.831 4.286 3.295 4.125
    Affymetric present call in "x" number of chips 2 3 2 3 3 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: serine-type endopeptidase activity.
There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; post-embryonic appendage morphogenesis; biological regulation; organ development; post-embryonic organ morphogenesis; response to chemical stimulus; learning or memory; cellular component organization or biogenesis; cell division; associative learning.
68 alleles are reported.
The phenotypes of these alleles are annotated with 160 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system subdivision; organ system; A1-7 oblique muscle; adult segment; larval abdominal segment 5; embryonic/larval neuron; primordium; A1-7 ventral oblique muscle 1; nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase S54, rhomboid; Peptidase S54, rhomboid domain; Peptidase S54, rhomboid, metazoan.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.