Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name R
Flybase description The gene Roughened is referred to in FlyBase by the symbol Dmel\R (CG1956, FBgn0004636).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.6341 3.5084 2.403702 2.8289 1.454478 2.4394 1.97725 1.863205
    Affimetrix absolute value 8.736 9.428 9.399 9.874 9.26 9.845 9.527 9.073
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; regulation of embryonic cell shape; germ-line stem cell maintenance; dorsal closure; hemocyte migration; cell adhesion; substrate-dependent cell migration, cell extension.
43 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; female germline cyst; nervous system; organ system; germarium; embryonic/larval hemocoel; hemocyte; cuticle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-12 hour embryonic stages.