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|Flybase description||The gene downstream of receptor kinase is referred to in FlyBase by the symbol Dmel\drk (CG6033, FBgn0004638).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; SH3/SH2 adaptor activity; sevenless binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; anatomical structure development; associative learning; learning or memory; learning; regulation of developmental process; cellular component organization or biogenesis; memory; embryonic development via the syncytial blastoderm; organ morphogenesis.
37 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; larval abdominal segment; abdominal lateral pentascolopidial chordotonal organ lch5; larval abdominal segment 5; adult segment; abdominal segment 7; abdominal 2 ventral monoscolopidial chordotonal organ vch1; imaginal precursor; external compound sense organ; abdominal 7 ventral monoscolopidial chordotonal organ vch1.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Neutrophil cytosol factor 2 p67phox; SH2 motif; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.