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|Flybase description||The gene hedgehog is referred to in FlyBase by the symbol Dmel\hh (CG4637, FBgn0004644).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cell surface binding; protein binding.
There is experimental evidence for 25 unique biological process terms, many of which group under: anatomical structure development; biological regulation; localization; organ morphogenesis; sensory organ development; cellular component organization or biogenesis; cellular process involved in reproduction; multicellular organismal reproductive process; organ development; locomotion.
177 alleles are reported.
The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: organ system subdivision; adult segment; primordium; late extended germ band embryo; adult mesothoracic segment; ventral nerve cord primordium; organ system; abdominal ventral denticle belt; imaginal precursor; germarium.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Hedgehog, N-terminal signaling domain; Hedgehog/DD-peptidase; Hedgehog/intein hint domain, C-terminal; Hedgehog/intein hint, N-terminal; Intein splice site; Peptidase C46, hedgehog protein; Peptidase C46, hedgehog protein, hint region.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.