Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fs(1)h
Flybase description The gene female sterile (1) homeotic is referred to in FlyBase by the symbol Dmel\fs(1)h (CG2252, FBgn0004656).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.6982 -1.2041 -1.970361 -2.4839 -3.88523 -2.9074 -2.87161 -3.883823
    Affimetrix absolute value 6.993 7.358 7.25 7.097 6.829 7.027 7.09 6.364
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: protein kinase activity; DNA binding.
There is experimental evidence that it is involved in the biological process: terminal region determination; negative regulation of transcription, DNA-dependent.
53 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic head; cephalopharyngeal skeleton; egg; metathoracic segment; mouth hooks; hypostomal sclerite.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Bromodomain; Bromodomain, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.