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|Flybase description||The gene single-minded is referred to in FlyBase by the symbol Dmel\sim (CG7771, FBgn0004666).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II core promoter proximal region sequence-specific DNA binding; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: adult walking behavior; positive regulation of transcription from RNA polymerase II promoter; axon guidance; determination of genital disc primordium; ventral midline development; brain development; axonogenesis; ventral cord development.
59 alleles are reported.
The phenotypes of these alleles are annotated with 86 unique terms, many of which group under: organ system subdivision; embryonic/larval neuron; VUM1 neuron; adult segment; presumptive embryonic/larval nervous system; VUM2 neuron; peripheral nervous system; primordium; late extended germ band embryo; multi-cell-component structure.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Nuclear translocator; PAC motif; PAS; PAS fold; PAS fold-3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.