Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name elB
Flybase description The gene elbow B is referred to in FlyBase by the symbol Dmel\elB (CG4220, FBgn0004858).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.7682 -3.0563 -4.030627 -3.4224 -6.501916 -5.0036 -3.9119 -4.012072
    Affimetrix absolute value 5.917 6.03 6.213 6.617 6.08 6.241 6.586 6.299
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: eye-antennal disc development; cell proliferation; Notch signaling pathway; open tracheal system development.
38 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; organ system subdivision; late extended germ band embryo; adult mesothoracic segment; primordium; tracheal branch primordium; non-connected developing system; thoracic segment; dorsal branch primordium; ganglionic branch primordium; organ system; external compound sense organ.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages.