Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name piwi
Flybase description The gene piwi is referred to in FlyBase by the symbol Dmel\piwi (CG6122, FBgn0004872).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.2919 2.3286 1.832005 1.609 1.221626 1.2488 -0.28274 1.481285
    Affimetrix absolute value 8.461 8.827 9.049 9.068 9.037 8.873 8.599 8.788
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; RNA binding.
There is experimental evidence that it is involved in the biological process: posttranscriptional gene silencing; male germ-line stem cell division; negative regulation of transposition, DNA-mediated; pole cell formation; stem cell division; female germ-line stem cell division; chromatin silencing.
27 alleles are reported.
The phenotypes of these alleles are annotated with: ovariole; egg; ovary; male germline stem cell; spectrosome; testis; nurse cell spectrosome; female germline stem cell; egg chamber; germarium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Argonaute/Dicer protein, PAZ; Ribonuclease H-like; Stem cell self-renewal protein Piwi.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.