Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name bowl
Flybase description The gene brother of odd with entrails limited is referred to in FlyBase by the symbol Dmel\bowl (CG10021, FBgn0004893).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.8523 -0.4052 -5.594444 -3.9996 -3.936808 -1.7838 -1.60638 -3.570023
    Affimetrix absolute value 7.519 7.528 5.696 6.413 6.802 7.744 7.877 6.45
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: wing disc development; hindgut morphogenesis; lateral inhibition; imaginal disc-derived leg morphogenesis; imaginal disc-derived leg joint morphogenesis.
31 alleles are reported.
The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; organ system subdivision; adult segment; embryonic hindgut; non-connected developing system; abdominal ventral denticle belt; cephalopharyngeal skeleton; appendage segment; embryonic segment; cuticle.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.