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|Flybase description||The gene Hepatocyte nuclear factor 4 is referred to in FlyBase by the symbol Dmel\Hnf4 (CG9310, FBgn0004914).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; ligand-dependent nuclear receptor activity.
There is experimental evidence that it is involved in the biological process: lipid catabolic process; lipid oxidation.
24 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Retinoid X receptor; Steroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, in stages of adults of both sexes.