Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name phm
Flybase description The gene phantom is referred to in FlyBase by the symbol Dmel\phm (CG6578, FBgn0004959).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.2787 -21.0778 -31.003396 -30.9376 -33.534069 -40.8187 -34.15613 -26.575764
    Affimetrix absolute value 3.544 3.256 3.264 3.436 3.748 3.226 3.457 3.511
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ecdysteroid 25-hydroxylase activity.
There is experimental evidence that it is involved in the biological process: embryonic development via the syncytial blastoderm; oogenesis; ecdysone biosynthetic process.
19 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: multicellular structure; organ system; non-connected developing system; presumptive embryonic/larval nervous system; anatomical structure; organ system subdivision; embryonic head; primordium; commissure; cuticle; presumptive embryonic/larval peripheral nervous system; portion of tissue; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.