Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gig
Flybase description The gene gigas is referred to in FlyBase by the symbol Dmel\gig (CG6975, FBgn0005198).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.0887 -2.0007 -2.871057 -2.4666 -4.550973 -2.5082 -2.61117 -3.58878
    Affimetrix absolute value 6.391 6.637 6.693 7.104 6.622 7.237 7.202 6.487
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; kinase binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: biological regulation; regulation of biological process; cellular component organization or biogenesis; response to chemical stimulus; response to stress; cellular response to stimulus; response to DNA damage stimulus; response to nutrient levels; cell-cell signaling; multicellular organismal reproductive process; determination of adult lifespan; signaling; primary metabolic process.
51 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; nervous system; adult mesothoracic segment; compound cell cluster organ; peripheral nervous system; eo support cell; rhabdomere; cell cycle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-type fold; Rap/ran-GAP; Tuberin; Tuberin-type domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.