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|Flybase description||The gene S-adenosylmethionine Synthetase is referred to in FlyBase by the symbol Dmel\Sam-S (CG2674, FBgn0005278).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: methionine adenosyltransferase activity.
There is experimental evidence that it is involved in the biological process: bristle development; wing disc development; S-adenosylmethionine biosynthetic process.
12 alleles are reported.
The phenotypes of these alleles are annotated with: eye; trichogen cell; macrochaeta; male genitalia; mesothoracic tergum; scutellar bristle; tergite.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase superfamily; S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, N-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.