Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ey
Flybase description The gene eyeless is referred to in FlyBase by the symbol Dmel\ey (CG1464, FBgn0005558).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.7226 -20.4151 -28.247364 -36.8309 -41.166936 -43.302 -35.96109 -28.509031
    Affimetrix absolute value 3.177 3.297 3.37 3.214 3.415 3.126 3.384 3.423
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding.
There is experimental evidence for 13 unique biological process terms, many of which group under: anatomical structure development; biological regulation; central nervous system development; organ development; multicellular organismal process; sensory organ development; neuron differentiation; organ morphogenesis; locomotory behavior; compound eye development.
62 alleles are reported.
The phenotypes of these alleles are annotated with 59 unique terms, many of which group under: organ system subdivision; adult segment; multi-cell-component structure; antennal segment; thoracic segment; external compound sense organ; imaginal precursor; presumptive embryonic/larval nervous system; lobula complex; dorsal thoracic disc; commissure.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.