Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sox14
Flybase description The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\Sox14 (CG3090, FBgn0005612).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.9702 -2.5242 -3.406885 -3.5271 -4.744787 -3.1633 -6.06371 -4.438685
    Affimetrix absolute value 6.101 6.298 6.458 6.591 6.597 6.94 5.98 6.126
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: dendrite morphogenesis; metamorphosis; neuron remodeling.
10 alleles are reported.
The phenotypes of these alleles are annotated with: dendrite; dorsal multidendritic neuron ddaC; mesothoracic tergum; anterior pupal spiracle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: High mobility group, HMG1/HMG2; High mobility group, superfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed during late larval stages, during early pupal stages.