Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name trpl
Flybase description The gene trp-like is referred to in FlyBase by the symbol Dmel\trpl (CG18345, FBgn0005614).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -34.7537 -16.3225 -26.853601 -29.0221 -36.76707 -31.0851 -35.60383 -23.307615
    Affimetrix absolute value 3.332 3.626 3.44 3.53 3.557 3.605 3.407 3.768
    Affymetric present call in "x" number of chips 0 3 1 0 0 0 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; calmodulin binding; calcium channel activity.
There is experimental evidence that it is involved in the biological process: calcium-mediated signaling; calcium ion transmembrane transport; body fluid secretion; calcium ion transport; cellular response to anoxia.
21 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; photoreceptor cell; Malpighian tubule; eye photoreceptor cell.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Ion transport; Transient receptor potential II; Transient receptor potential channel; Transient receptor potential channel, canonical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed in adult male stages.