Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name robo
Flybase description The gene roundabout is referred to in FlyBase by the symbol Dmel\robo (CG13521, FBgn0005631).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.6283 -6.5289 -14.408986 -9.6041 -20.856551 -10.2147 -12.31192 -18.579158
    Affimetrix absolute value 5.307 4.938 4.359 5.176 4.429 5.235 4.947 4.173
    Affymetric present call in "x" number of chips 3 2 1 3 1 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: heparin binding; protein binding.
There is experimental evidence for 17 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; locomotion; organ development; organ morphogenesis; regulation of biological process; neuromuscular process; taxis; dendrite morphogenesis.
53 alleles are reported.
The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: organ system subdivision; nervous system; embryonic/larval neuron; multi-cell-component structure; hypodermal muscle of larval abdomen; commissure; peripheral nervous system; presumptive embryonic/larval nervous system; A1-7 transverse muscle; sensillum; cell projection.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.