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|Flybase description||The gene roundabout is referred to in FlyBase by the symbol Dmel\robo (CG13521, FBgn0005631).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: heparin binding; protein binding.
There is experimental evidence for 17 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; locomotion; organ development; organ morphogenesis; regulation of biological process; neuromuscular process; taxis; dendrite morphogenesis.
53 alleles are reported.
The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: organ system subdivision; nervous system; embryonic/larval neuron; multi-cell-component structure; hypodermal muscle of larval abdomen; commissure; peripheral nervous system; presumptive embryonic/larval nervous system; A1-7 transverse muscle; sensillum; cell projection.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.