Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name faf
Flybase description The gene fat facets is referred to in FlyBase by the symbol Dmel\faf (CG1945, FBgn0005632).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.7449 -3.4751 -7.519056 -4.62 -13.032339 -5.1715 -4.80127 -11.100778
    Affimetrix absolute value 4.878 5.823 5.345 6.217 5.124 6.207 6.332 4.917
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: ubiquitin-specific protease activity.
There is experimental evidence that it is involved in the biological process: mystery cell differentiation; protein deubiquitination; compound eye development; embryo development; cellularization; nuclear migration; ubiquitin-dependent protein catabolic process.
55 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system subdivision; external compound sense organ; nervous system; synapse; adult segment; peripheral nervous system; multi-cell-component structure; eo support cell; blastoderm embryo; cytoplasmic part; adult mesothoracic segment.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Armadillo-type fold; Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2; Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.