Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name comm
Flybase description The gene commissureless is referred to in FlyBase by the symbol Dmel\comm (CG17943, FBgn0010105).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.2046 -2.3788 -11.789772 -12.4577 -18.181364 -14.0413 -1.64021 -6.979215
    Affimetrix absolute value 8.673 6.402 4.66 4.799 4.578 4.761 7.867 5.523
    Affymetric present call in "x" number of chips 3 3 0 1 0 1 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: WW domain binding; protein binding.
There is experimental evidence that it is involved in the biological process: synapse assembly; receptor internalization; positive regulation of receptor internalization; axon guidance; dendrite morphogenesis; axon midline choice point recognition; neuron recognition; dendrite guidance.
72 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; embryonic/larval neuron; commissure; multi-cell-component structure; nervous system; peripheral nervous system; presumptive embryonic/larval nervous system; thoracic segment; embryonic/larval tracheal system; synaptic neuropil subdomain; cell projection; ganglionic branch primordium; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.