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|Flybase description||The gene commissureless is referred to in FlyBase by the symbol Dmel\comm (CG17943, FBgn0010105).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: WW domain binding; protein binding.
There is experimental evidence that it is involved in the biological process: synapse assembly; receptor internalization; positive regulation of receptor internalization; axon guidance; dendrite morphogenesis; axon midline choice point recognition; neuron recognition; dendrite guidance.
72 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: organ system subdivision; embryonic/larval neuron; commissure; multi-cell-component structure; nervous system; peripheral nervous system; presumptive embryonic/larval nervous system; thoracic segment; embryonic/larval tracheal system; synaptic neuropil subdomain; cell projection; ganglionic branch primordium; antennal segment.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.