Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Lac
Flybase description The gene Lachesin is referred to in FlyBase by the symbol Dmel\Lac (CG12369, FBgn0010238).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.9605 1.9404 -18.85644 -17.9614 -23.531823 -7.4752 3.58647 -3.046524
    Affimetrix absolute value 9.966 8.567 4.0 4.245 4.201 5.735 10.334 6.73
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: morphogenesis of embryonic epithelium; homophilic cell adhesion; regulation of tube size, open tracheal system; maintenance of epithelial integrity, open tracheal system; open tracheal system development.
14 alleles are reported.
The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; dorsal group branch precursor; embryonic/larval dorsal trunk; presumptive embryonic/larval tracheal system; embryonic/larval tracheal system; lateral group branch precursor; dorsal trunk primordium; embryonic/larval transverse connective.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.