Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Taf4
Flybase description The gene TBP-associated factor 4 is referred to in FlyBase by the symbol Dmel\Taf4 (CG5444, FBgn0010280).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.9994 -1.3115 -2.419197 -2.3939 -3.647901 -2.1596 -2.65077 -3.453647
    Affimetrix absolute value 6.829 7.231 6.906 7.159 6.903 7.452 7.22 6.507
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; dendrite morphogenesis; muscle organ development; neurogenesis.
26 alleles are reported.
No phenotypic data is available.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Histone-fold; TAFH/NHR1; Transcription initiation factor TFIID component TAF4.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.