|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene brain tumor is referred to in FlyBase by the symbol Dmel\brat (CG10719, FBgn0010300).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; translation repressor activity.
There is experimental evidence for 16 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; cell division; cellular macromolecule metabolic process; cell fate commitment; cell fate determination; ncRNA metabolic process; neuroblast fate commitment; multicellular organismal reproductive process; gene expression; multicellular organismal process.
105 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; organ system subdivision; germarium; female germline cyst; multicellular structure; nervous system; somatic cell; embryonic abdomen; embryonic segment; imaginal precursor; external compound sense organ; adult segment.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like; Zinc finger, B-box.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.