Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dap
Flybase description The gene dacapo is referred to in FlyBase by the symbol Dmel\dap (CG1772, FBgn0010316).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.287 -3.3239 -5.609678 -6.8664 -7.940322 -5.8178 -4.16211 -6.249032
    Affimetrix absolute value 6.706 5.888 5.704 5.624 5.781 6.03 6.508 5.599
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cyclin-dependent protein kinase inhibitor activity.
There is experimental evidence that it is involved in the biological process: germarium-derived oocyte fate determination; histoblast morphogenesis; G1 phase; negative regulation of S phase of mitotic cell cycle; negative regulation of protein dephosphorylation; sensory organ precursor cell division.
33 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; eo support cell; egg; external compound sense organ; nervous system; organ system; embryonic/larval tracheal system; sensillum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cyclin-dependent kinase inhibitor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages.