Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Cdc42
Flybase description The gene Cdc42 is referred to in FlyBase by the symbol Dmel\Cdc42 (CG12530, FBgn0010341).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.388 5.0061 3.693541 6.4804 2.265474 3.5706 1.87912 3.457426
    Affimetrix absolute value 8.865 9.926 10.049 11.071 9.913 10.391 9.449 9.955
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 19 unique biological process terms, many of which group under: cellular component organization or biogenesis; anatomical structure development; biological regulation; establishment or maintenance of cell polarity; localization; actin filament-based process; regulation of multicellular organismal development; synaptic transmission; regulation of developmental process; locomotion; wound healing.
42 alleles are reported.
The phenotypes of these alleles are annotated with 53 unique terms, many of which group under: organ system subdivision; adult segment; organ system; nervous system; embryonic/larval neuron; cell projection; somatic cell; external compound sense organ; late extended germ band embryo; female germline cyst; ectoderm derivative; axon.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.