Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Nc73EF
Flybase description The gene Neural conserved at 73EF is referred to in FlyBase by the symbol Dmel\Nc73EF (CG11661, FBgn0010352).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.295 6.096 3.902803 9.2115 1.440782 2.9252 10.13476 3.811944
    Affimetrix absolute value 10.096 10.203 10.095 11.575 9.277 10.105 11.885 10.065
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: oxoglutarate dehydrogenase (succinyl-transferring) activity.
Based on sequence similarity, it is predicted to be involved in the biological process: tricarboxylic acid cycle.
7 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: 2-oxoglutarate dehydrogenase, E1 component; Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.