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|Flybase description||The gene TBP-associated factor 1 is referred to in FlyBase by the symbol Dmel\Taf1 (CG17603, FBgn0010355).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding; histone serine kinase activity.
There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription involved in G2/M-phase of mitotic cell cycle; regulation of JAK-STAT cascade; histone acetylation; neurogenesis.
30 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; organ system; adult segment; sensillum; female germline cyst; external compound sense organ; adult mesothoracic segment; integumentary plate; gamete; peripheral nervous system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: AT hook, DNA-binding motif; Bromodomain; Bromodomain, conserved site; TAFII-230 TBP-binding; Transcription initiation factor TFIID subunit 1, animal; Transcription initiation factor TFIID subunit 1, domain of unknown function; Zinc finger, CCHC-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.