Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Akt1
Flybase description The gene Akt1 is referred to in FlyBase by the symbol Dmel\Akt1 (CG4006, FBgn0010379).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.2925 0.39 -1.591079 -1.4596 -2.521596 -1.6262 -1.71443 -1.827099
    Affimetrix absolute value 7.219 7.688 7.509 7.85 7.424 7.873 7.816 7.394
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity; protein kinase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; anatomical structure development; regulation of biological process; macromolecule modification; cellular component organization or biogenesis; localization; regulation of developmental process; positive regulation of biological process; regulation of cellular component organization; protein modification process; lipid storage; chitin-based cuticle development; open tracheal system development; regulation of apoptosis; regulation of multicellular organismal development; response to hormone stimulus.
32 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; thoracic segment; organ system; compound cell cluster organ; gland; wing hair; dorsal thoracic disc; primordium; synapse.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.