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|Flybase description||The gene Akt1 is referred to in FlyBase by the symbol Dmel\Akt1 (CG4006, FBgn0010379).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity; protein kinase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; anatomical structure development; regulation of biological process; macromolecule modification; cellular component organization or biogenesis; localization; regulation of developmental process; positive regulation of biological process; regulation of cellular component organization; protein modification process; lipid storage; chitin-based cuticle development; open tracheal system development; regulation of apoptosis; regulation of multicellular organismal development; response to hormone stimulus.
32 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; thoracic segment; organ system; compound cell cluster organ; gland; wing hair; dorsal thoracic disc; primordium; synapse.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.