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|Flybase description||The gene RNA polymerase II elongation factor is referred to in FlyBase by the symbol Dmel\TfIIS (CG3710, FBgn0010422).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: translation elongation factor activity; DNA binding; zinc ion binding.
Based on sequence similarity, it is predicted to be involved in the biological process: regulation of transcription, DNA-dependent.
8 alleles are reported.
The phenotype of these alleles is annotated with: wing.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Transcription elongation factor S-II, central domain; Transcription elongation factor S-IIM; Transcription elongation factor, IIS; Transcription elongation factor, TFIIS; Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type; Transcription factor IIS, N-terminal; Zinc finger, TFIIS-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.